Pathologic Changes After Photodynamic Therapy for Basal Cell Carcinoma and Bowen Disease
نویسندگان
چکیده
منابع مشابه
Photodynamic therapy for large or multiple patches of Bowen disease and basal cell carcinoma.
BACKGROUND Photodynamic therapy (PDT) using topical delta-aminolevulinic acid (delta-ALA) is an effective treatment for Bowen disease and certain basal cell carcinomas (BCCs), but its place in clinical practice remains to be established. Patients with large and/or multiple lesions of Bowen disease or BCC can represent a considerable therapeutic challenge. We suggest that delta-ALA PDT may be of...
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Background: Basal Cell Carcinoma (BCC) is the most common type of skin cancer in human beings. Photodynamic therapy (PDT) is a novel therapeutic method which may be regarded as a non-invasive useful alternative for traditional treatments of BCC. This study was designed with the aim of evaluating the primary response of BCC to PDT.Methods: This clinical trial was perform...
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Photodynamic therapy (PDT) is a medical procedure based on the activation of the molecules of various exogenous or endogenous chemical substances called photosensitizers by a light source emitting radiation of an adequate wavelength, usually situated in the visible spectrum; photosensitizers are chemical compounds bearing the capacity to selectively concentrate in the neoplastic cells. The ener...
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Photodynamic therapy (PDT) involves the activation of a photosensitizing drug by visible light to produce activated oxygen species which promote tumour destruction. Despite a rising tide of publications in recent years, PDT was first described 100 years ago. Generalized and severe phototoxicity from early crude photosensitizers limited development, although partial purification produced a haema...
متن کاملOcular changes after photodynamic therapy.
PURPOSE The aim of this study was to identify the changes in the primate visual system after a single session of photodynamic therapy (PDT) in an intact nonhuman primate retina. METHODS As part of a larger study, PDT (wavelength 689 nm, 50 J/cm2, 600 mW/cm2, 83 seconds, 4-mm spot size) with verteporfin (6 mg/m2 intravenous infusion) was performed in one eye each of two cynomolgus monkeys. Fun...
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ژورنال
عنوان ژورنال: Archives of Dermatology
سال: 2008
ISSN: 0003-987X
DOI: 10.1001/archdermatol.2007.31